Tobias Ritter

Aliphatic Diazonium Chemistry through Hydroquinone-Based Nitrate Reduction for Deaminative Halogenation and Nitrate Ester Formation

Abstract Alcohols are readily converted to electrophiles on a large scale, while deaminative functionalization of aliphatic amines is less developed. Aromatic amines are readily used as versatile synthetic intermediates through diazonium chemistry, but analogous aliphatic diazoni...

Modular synthesis of 3,3-diaryloxetanes

Abstract Oxetanes are strained four-membered oxygen heterocycles that are valuable motifs for modulating lipophilicity, metabolic stability and three-dimensional structure of pharmaceuticals. Diaryloxetanes with 3,3-substitution are recognized as bioisosteres of diaryl ketones th...