Timothy Lynagh

Molecular Determinants of Ligand Selectivity in Diverse Ionotropic Glutamate Receptors

Abstract Ionotropic glutamate receptors (iGluRs) mediate rapid signals between neurons by binding extracellular neurotransmitters and conducting ionic current across the cell membrane. Animal iGluRs can be divided into clades of phylogenetically related receptors, only some of wh...