Timothy L. Tellinghuisen

In vitro and in vivo model systems for Orthoflavivirus antiviral therapeutics: current landscape and strategic considerations

ABSTRACT Orthoflaviviruses represent an escalating global health challenge, encompassing a diverse group of arthropod-borne viruses that cause substantial morbidity and mortality worldwide. A critical bottleneck in drug discovery is identifying in vitro and in vivo models that ac...