Tiantian Sang

Osteoclastogenesis with FN1-associated cell differentiation, immune communication, and ECM remodeling in male SAMP6 mice

Early diagnosis and precise treatment of senile osteoporosis remain challenging. Herein, we apply a multi-omics strategy, integrating scRNA-seq and proteomics in the male 5-month-old senescence-accelerated mouse prone 6 (SAMP6) spontaneous aging model, to study early bone loss. T...