Tianlu Chu

An aging-informed multi-layer bioinformatics framework prioritizes GKN1 and PLAU/uPA-associated candidates in gastric cancer

Gastric cancer is molecularly heterogeneous. We used curated aging-gene annotation as a candidate-filtering prior, rather than as evidence of an aging mechanism, within an integrated bulk and single-cell bioinformatics framework. Differentially expressed genes in GSE29272 were in...