Thusini Uggalla Arachchige

Elucidating the Requirements for microRNA-Mediated Upregulation Enables Reengineering of Upregulatory Sites

Abstract The post-transcriptional regulation of protein expression by miRNA has given rise to new technologies for therapeutic interventions and synthetic biology. To date, these technologies assume that miRNAs are repressors of protein expression; however, emerging evidence has...