Thotanolla Surya Prakash

Fatal tumor lysis syndrome presenting with extreme hyperuricemia and dialysis-requiring acute kidney injury in blast-phase chronic myeloid leukemia

Tumor lysis syndrome (TLS) is a life-threatening oncologic emergency characterized by hyperuricemia, hyperphosphatemia, hyperkalemia, hypocalcemia, and acute kidney injury (AKI). Although TLS most commonly occurs following initiation of cytotoxic therapy, it may rarely develop sp...

Massive Aseptic Splenic Abscess as the Presenting Manifestation of Active Lupus Nephritis: A Case Report

Splenic abscesses are uncommon in systemic lupus erythematosus (SLE) and are typically infectious. Aseptic abscesses—sterile purulent collections resulting from immune dysregulation—are exceedingly rare and diagnostically challenging. We report a 25-year-old woman with no prior r...