Thomas Wild

The SPATA5-SPATA5L1-CINP-C1ORF109 complex is essential for cytoplasmic pre-60S ribosome maturation

The ribosome is a universally conserved and essential molecular machine. While the core process of ribosome biogenesis is conserved across eukaryotes, metazoans have evolved additional regulatory factors. Here, we performed a protein–protein interaction screen of endogenously aff...