Thomas Sherlock

Focused ultrasound-mediated opening of the blood brain barrier for non-invasive drug delivery to the murine cerebellum

Abstract Background The blood brain barrier (BBB) limits effective treatment for cerebellar diseases. Region-specific parameterization and safety data for MRI-guided focused ultrasound (MRgFUS) BBB opening (BBBO) in the cerebellum are scarce. The goal of this study is to establis...