Thomas P. Conrads

Histology resolved proteomic characterization of the triple negative breast cancer tumor immune microenvironment

Treatment options for the highly aggressive triple-negative breast cancer (TNBC) subtype remain limited, though the immune microenvironment represents a promising therapeutic target. We conducted a histology resolved tumor microenvironment analysis of TNBC by employing deep quant...

Proteogenomic profiling defines progression-associated biology in high-risk endometrial cancer

Patients with high-risk endometrial carcinoma (HR-EC) experience substantial mortality despite multimodality therapy, molecular classification and contemporary care. We determined whether proteomic tumor programs capture lethal risk beyond established clinical and genomic classif...