Thomas Kuntz

Gut microbiome–metabolome interactions during varied low-carbohydrate food consumption

Low-carbohydrate (LC) foods have been associated with weight loss, insulin resistance, and reduced inflammation. Gut microbes may drive these effects by changing the host’s immune and metabolic state, yet the optimal replacement strategies (e.g., protein vs. fat) and the biochemi...

Shotgun Metagenomics Identify Unique Changes of the Intestinal Microbiome in Pediatric Survivors of Acute Lymphoblastic Leukemia.

BACKGROUND: Intestinal microbiota plays an important role in human health and metabolism. Microbial dysbiosis has been observed in various chronic conditions, many of which are late effects of leukemia treatment. We previously observed significant differences in the gut microbiom...