Thilo Burkard

Improving heart failure care in rural Africa: overcoming implementation barriers

Abstract In this narrative review, we present the most important heart diseases causing heart failure in sub-Saharan Africa, discuss challenges, uncertainties and research gaps, and suggest strategies to lower the burden of disease. Hypertensive heart disease is the most common c...

Angiotensin peptide and aldosterone concentrations in response to four classes of blood‐pressure-lowering drugs in hypertensive patients: A randomized trial

Abstract The renin angiotensin aldosterone system (RAS) regulates blood pressure and fluid balance by a cascade of angiotensin (Ang) peptides. Antihypertensive drug classes differentially modulate this cascade. This study examined how four mechanistically distinct antihypertensiv...