Thierry Pourcher

Evidence-Tiered Venomics of the BotG50 Toxic Fraction from Buthus tunetanus Reveals a Diversified Neurotoxin Repertoire

Scorpion venoms represent complex pharmacological arsenals whose complete molecular inventory remains incompletely defined, particularly for North African buthid species of high medical relevance. Buthus tunetanus is among the most clinically significant scorpion species across t...

Comprehensive proteomic and structural mapping of post-translational modifications of human thyroglobulin

Human thyroglobulin (hTg) is the precursor of thyroid hormones (TH) and a major iodine reservoir in the thyroid gland. Its maturation and function critically depend on multiple post-translational modifications (PTMs). To date, their global distribution, structural organization an...