Thierry P. P. van den Bosch

Transient (Pro)renin receptor silencing disrupts proximal tubule development in human kidney organoids

The (pro)renin receptor [(P)RR] plays a crucial role in murine kidney development, but its function in human kidneys remains poorly understood due to the lack of suitable research models. Human induced pluripotent stem cell (iPSC)-derived kidney organoids recapitulate early kidne...