Theresa M. Kisko

Dual Role of CACNA1C/CaV1.2 in Cardiac and Neuropsychiatric Disease

The CACNA1C gene encodes the α1C subunit of voltage-gated CaV1.2 calcium channels, serving many pivotal functions throughout the body, including in the heart and brain. Clinical and genetic evidence implicates altered expression and/or function of CACNA1C/CaV1.2 in both cardiac a...