Thang H. Nguyen

Context- and Cell-Dependent Roles of S1PR1 in Atherosclerosis: Therapeutic Implications of Selective S1PR1 Modulation

Abstract Sphingosine 1-phosphate receptor 1 (S1PR1) regulates vascular homeostasis and immune function, but its role in atherosclerosis has remained controversial because activating the same receptor produces divergent effects across cell types. This review synthesizes evidence o...