Tetsutaro Yamaguchi

Association of PTH1R Gene Polymorphisms with Three-Dimensional Mandibular Morphology Across Three Recruitment Cohorts

Parathyroid hormone 1 receptor (PTH1R) regulates chondrocyte differentiation and mandibular condylar cartilage development, but its contribution to adult mandibular morphology remains unclear. We investigated associations of two PTH1R single-nucleotide polymorphisms (SNPs), rs724...

DNA methylation changes following rapid maxillary expansion in children

Rapid maxillary expansion (RME) is a widely used orthodontic intervention for correcting transverse maxillary deficiencies. By mechanically separating the midpalatal suture, RME improves occlusal relationships and induces tissue repair processes similar to fracture healing. Infla...