Takeyuki Shindo

Association Between Efficacy and Pharmacokinetics of DMB-3115 and its Originator Ustekinumab in Patients with Chronic Plaque Psoriasis: An Exposure–Response Analysis

DMB-3115 is a biosimilar to ustekinumab (Stelara ® ). Although a single-dose study conducted in Europe showed that the pharmacokinetics of DMB-3115 was equivalent to that of ustekinumab, another single-dose study in Japan suggested that the maximum serum concentration ( C max ) o...