Takeshi Uehara

NOTCH1 activating variants identify a high-risk subgroup of adenoid cystic carcinoma in a nationwide Japanese cohort

Abstract Adenoid cystic carcinoma (ACC) follows a heterogeneous clinical course, and because systemic therapies have limited efficacy, active surveillance is offered to selected patients, yet no validated molecular biomarker guides the choice between surveillance and intensive tr...

Loss of SATB2 is associated with MUC16 upregulation in the invasive component of colitis-associated colorectal carcinoma

Colitis-associated colorectal carcinoma (CAC) arises in the setting of long-standing inflammatory bowel disease and shows clinicopathological and molecular differences from sporadic colorectal carcinoma. Loss of SATB2 expression is increasingly recognized in a subset of CACs, but...