Takeshi Hashimoto

A novel machine-learning model using nuclear features to predict upper tract urothelial carcinoma recurrence

Abstract Upper-tract urothelial carcinoma (UTUC) is rare, constitutes < 5% of urothelial cancers, and, given its insidious clinical presentation, is typically diagnosed at advanced stages; post-radical nephroureterectomy recurrence remains challenging. Postoperative management is...

Predictors of renal function decline during platinum-based chemotherapy in advanced urothelial carcinoma

Abstract Background Platinum-based chemotherapy remains the cornerstone treatment for advanced urothelial carcinoma (aUC). However, treatment selection is often influenced by baseline renal function. Gemcitabine plus carboplatin (GCa) is widely used in patients who are considered...