Takanori Sasaki

Cross-disease immunological comparison reveals shared systemic immune activation across the broader spondyloarthritis spectrum

To perform cross-disease immunological comparison across the broader spondyloarthritis (SpA) spectrum and examine their association with disease activity. We analyzed 111 patients with active broader SpA spectrum (ankylosing spondylitis, inflammatory bowel disease–associated SpA,...

Autoantibody Clusters and SIGLEC1 are Predictive of Systemic Lupus Erythematosus Development

Objectives Up to one-third of patients with suspected SLE progress to definite disease, but reliable predictive markers are lacking. Previously, we developed a Lupus Lymphocyte Activation Score (LLAS) based on key cell subsets (transitional B cells, age-associated B cells, plasma...