Taha Ibrahim

Safety and efficacy of evobrutinib in relapsing multiple sclerosis: a GRADE-assessed systematic review and meta-analysis

Background Bruton’s tyrosine kinase (BTK) inhibitors are emerging as a potential therapy for multiple sclerosis (MS) by targeting both peripheral and central nervous system–compartmentalized inflammation. Evobrutinib is the first BTK inhibitor evaluated in randomized controlled t...

Efficacy and Safety of Baxdrostat in Hypertension: A GRADE-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials

BACKGROUND: Baxdrostat, a selective aldosterone synthase inhibitor, has emerged as a novel therapy for uncontrolled or resistant hypertension; however, randomized controlled trials (RCTs) have shown variable results. OBJECTIVE: To evaluate the efficacy and safety of baxdrostat co...