T R Shende

Temporal effects of Palmitoylethanolamide (PEA) in modulating knee osteoarthritis symptoms: A randomized, double-blind, placebo-controlled trial

Background Osteoarthritis involves cartilage degradation, driven by elevated matrix metalloproteinases and inflammatory signalling, while available therapies offer only symptomatic relief. Palmitoylethanolamide (PEA), an endogenous fatty acid amide with anti-inflammatory and anal...