Syeda Ummul Khair Fatima

Integrative machine learning reveals telomere-associated gene modules reflecting neuronal dysregulation in Alzheimer's disease

Background Telomere dysfunction contributes to cellular aging and genome instability, but telomere-associated transcription in Alzheimer's disease (AD) is poorly characterized. Telomere genes are commonly tested gene by gene, leaving it uncertain whether they organize into reprod...