Suwan Ding

Intracranial delivery of neuron-preferential lipid nanoparticles for gene-editing activity in mouse brain

Lipid nanoparticles (LNPs) are promising non-viral vectors for central nervous system (CNS) gene therapy, but effective delivery is limited by the blood-brain barrier and cell-type specificity. Here, we combined intracranial delivery with high-throughput, cluster-based screening...