Suvaiyarasan Suvaithenamudhan

Bulk transcriptomics of peripheral blood mononuclear cells delineates systems-level immune dysregulation in pediatric dengue infection

Abstract Children are disproportionately at a greater risk of developing severe dengue disease, yet the molecular mechanisms driving the heightened susceptibility remains poorly understood. To elucidate the immune determinants of pediatric dengue pathogenesis, we profiled the tra...