Susmita Chowdhuri

Acetazolamide Mitigates Opioid-Associated Sleep-Disordered Breathing

Rationale: Chronic prescription opioid use can exert ventilatory depression and increase loop gain to induce sleep disordered breathing (SDB). Alternative therapies to mitigate opioid-associated SDB are needed. Objective: We sought to examine whether oral acetazolamide (ACZ) will...