Author
Susanne Ziegler
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Recent research
- BiologyOpen access
Cullin 3 ubiquitin ligase regulates redox defense and metabolic programs in proximal tubule cells
Abstract Background Chronic kidney disease (CKD) is characterized by proximal tubule (PT) stress, oxidative injury, and metabolic dysfunction. Human kidney single-nucleus RNA-sequencing (snRNA-seq) identified enrichment of ubiquitin-dependent protein catabolic processes in injure...