Author
Susan M. Domchek
Recent research
- Health & MedicineOpen access
Structured Abstract Background Women at risk of ovarian cancer due to BRCA1/2 pathogenic variants are advised to undergo bilateral risk-reducing salpingo-oophorectomy (RRSO) prior to natural menopause. Epidemiologic evidence suggests that surgical menopause increases cardiovascul...
- BiologyOpen access
Abstract Background Germline cancer genetic testing has become a standard evidence-based practice, with established risk reduction and cancer screening guidelines for genetic carriers. There are also targeted treatments for some genetic carriers with cancers such as breast and ov...