Sundaresan Sivapatham

Mechanistic integration of genetic alterations, PTM signaling, and tumor microenvironment remodeling in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies, with late diagnosis, rapid progression, considerable therapy resistance, and low overall survival. Growing evidence suggests that PDAC progression is not determined by simple genetic events but rather d...