Sundarababu Baskaran

An ″α-Methylsulfone″ Transfer Agent: Synthesis and Application of γ-Ketosulfones

Abstract An operationally simple, metal-free one-pot method for the synthesis of γ-ketosulfone from ketone has been developed using aryl/alkyl sulfonyl hydrazide-formaldehyde as an ″α-methylsulfone″ transfer agent. This one-carbon elongation method, promoted by a TFA-morpholine s...

Copper(II)/4‐Dimethylaminopyridine‐Mediated Oxidative Cyclization in Low‐Melting Mixtures: Access to Cyclopropane‐Fused Aza‐Heterocycles

A simple and efficient one‐pot approach has been developed for the stereoselective synthesis of 3‐azabicyclo[n.1.0]alkane derivatives, employing a low–melting mixture (LMM) composed of choline chloride (ChCl) and N , N ‐dimethylurea (DMU). This green and sustainable protocol faci...