Sunaina Sardana

Strain-release photocatalytic access to rigidified isosteres of bicyclic heterocycles

We present the synthesis of fused isoxazolidine-pyrrolidine architectures via a dual rigidification strategy. These frameworks are accessed through an atom-economical approach using variously substituted isoxazolines and bicyclo[1.1.0]butane (BCB) derivatives under mild condition...