Steven De Jonghe

Repurposing Thiazole/Benzothiazole-Based Thiazolidinone Derivatives as SARS-CoV-2 Main Protease (Mpro) Inhibitors: An Integrated Computational and Experimental Study

Background/Objectives: SARS-CoV-2, the causative agent of COVID-19, relies on its main protease (Mpro) for viral replication, making this enzyme an attractive target for antiviral drug development. In the present study, we investigated whether a library of previously synthesized...