Stephen B. Kritchevsky

Adiposity and Cognitive Performance in Older Men and Women from the Study of Muscle, Mobility and Aging (SOMMA)

BACKGROUND: Aging is accompanied by changes in body composition and cognition. Although adiposity has been linked to metabolic dysfunction and dementia risk, associations with specific cognitive domains in later life remain unclear. METHODS: This cross-sectional study examined as...

Impact of caloric restriction on biological aging: insights from a composite biomarker index in older adults

Abstract Caloric restriction (CR) extends lifespan and delays age-related diseases in model organisms, yet its effects on biological aging in humans remain unclear. We pooled data from seven randomized CR trials ( n = 829) and examined randomization to CR and change in weight wit...