Stephan Ossowski

Spatial transcriptomics profiling across tissue boundaries in the developing mouse brain

Tissue boundaries preserve structural integrity and guide cell differentiation during development, despite constant stress from proliferation, cell death, and tissue deformation. To study gene regulation in these regions we developed REBOSEP, a workflow for analyzing spatial tran...

aiDIVA – hybrid AI for rare disease diagnostics using evidence-based, machine learning and language models

Abstract Genome sequencing enables accurate detection of genetic variants and is transforming rare disease diagnostics. While data generation is scalable, prioritization and clinical interpretation remain challenging, often requiring expert manual classification. AI-driven decisi...