Stefano Pagliara

Prophage and metabolic determinants of Staphylococcus aureus survival to vancomycin identified via TraDIS screening

ABSTRACT Reduced vancomycin susceptibility phenotypes in Staphylococcus aureus contribute to treatment failure, yet the genetic determinants of survival under inhibitory vancomycin exposure remain incompletely defined. We performed transposon-directed insertion-site sequencing (T...

A mechanistically inspired geometric model to predict microbial growth across environments

Abstract Estimating bacterial growth trajectories is essential for bridging mechanistic insights and experimental data. Nevertheless, widely used empirical models tend to be overly simplistic or purely phenomenological. Mechanistic models offer greater detail but still fall short...