Song Chen

Small-Molecule-Directed RNA Modification via Proximity-Driven Catalysis

Abstract Selective chemical modification of RNA is essential for RNA functionalization, probing RNA structure–function relationships and developing RNA-targeted therapeutics. Existing chemical strategies often rely on guanine accessibility or multiple helper DNA strands, restrict...

Nitro Reduction‐Based RNA Control and Ultrafast Release

ABSTRACT RNA protection and controlled release are critical for both fundamental research and therapeutic applications, yet the development of simple, efficient, and reversible post‐synthetic RNA modification strategies remains a significant challenge. Here, we introduce a straig...

Nitro Reduction‐Based RNA Control and Ultrafast Release

RNA protection and controlled release are critical for both fundamental research and therapeutic applications, yet the development of simple, efficient, and reversible post-synthetic RNA modification strategies remains a significant challenge. Here, we introduce a straightforward...