Siyuan Huang

Reprogramming pulmonary B cells by ANXA1 silencing halts lung metastatic niche formation in breast cancer

Lung metastasis remains a determinant of poor prognosis and survival in breast cancer and is understood to depend on a permissive pulmonary immune niche rather than tumor cell traits alone. Here, we developed a host-directed RNA interference strategy to modulate this niche by rep...