Siyan Qiu

Cycloaddition EnablesRing Opening of N -Propargyl Oxazolidines:Access to N -Benzyl-2,3-diphenylpyrrolesvia Both C–O and C–C Bond Cleavage

Abstract Aza-diarylmethanes represent a privileged class of pharmacophores found in numerous bioactive molecules. However, conventional synthetic approaches often suffer from the need for prefunctionalized starting materials, harsh reaction conditions, and limited substrate compa...