Simone Matteo Negrini

Beyond monospecificity in systemic lupus erythematosus: Emerging roles of bispecific and trispecific antibodies

Purpose Targeted biologic therapy has changed the management of systemic lupus erythematosus (SLE), including lupus nephritis (LN), but incomplete response, relapse, glucocorticoid dependence, and refractory organ disease remain common. This article discusses whether bispecific a...

Diagnostic Performance of Source-Recorded Food-Specific Prick-by-Prick Testing Against Oral Food Challenge Outcomes: A Challenge-Selected Single-Center Retrospective Study

Oral food challenge (OFC) is the reference standard for diagnosing IgE-mediated food allergy, whereas the performance of prick-by-prick testing (PbP) with native foods in routine care is uncertain. We retrospectively screened all food-specific OFC records from 2 January 2024 to 6...