Simone Grimm

Ketamine’s impact on rumination-related brain dynamics: insights from a randomized controlled fMRI trial

Abstract Rumination has been associated with aberrant dynamics of a coactivation pattern (CAP) comprising the default mode (DMN) and frontoparietal (FPN) networks. Ketamine exerts rapid antidepressant effects and may influence these dynamics via glutamatergic mechanisms. In a ran...