Simone D I FRANCO

P1.105. Epithelial–Mesenchymal Plasticity Underlies Adaptive Resistance to FLOT Chemotherapy in Esophageal Adenocarcinoma

Abstract Topic Esophageal Cancer: Molecular Biology/Pathology Background Resistance to perioperative FLOT chemotherapy remains a major determinant of poor outcome in esophageal adenocarcinoma. Epithelial–mesenchymal plasticity (EMP) enables dynamic cell state transitions that may...