Simon Heilbronner

A single transcriptional regulator is crucial for the adaptation of Staphylococcus aureus to diverse niches

Adaptation of bacterial pathogens to new hosts often involves the exchange of mobile genetic elements, or generally the highly variable accessory genome. However, adaptation to different niches is often plastic, mediated by conserved pathways in the core genome. The general stres...

Community composition drives metabolic competition and Staphylococcus aureus colonization resistance in synthetic nasal communities

Abstract The human nasal microbiome is a low-diversity ecosystem whose assembly principles and mechanisms of colonization resistance remain poorly understood. Staphylococcus aureus is a member of the nasal microbiome of some individuals with variable abundance. We hypothesized th...