Author
Simon J. Haworth
Recent research
- Health & MedicineOpen access
Cross-platform, multi-cohort identification of a caries microbial signature
Objective To identify a robust salivary microbial signature associated with caries using a cross-platform, multi-cohort design.Design Full-length 16S rRNA gene sequencing (ONT) and shotgun metagenomics (MET) were performed in a derivation cohort with matched data (n = 463). Assoc...
- Health & MedicineOpen access
Life stage shifts in salivary microbiota determinants: a cross-sectional study in twins
Abstract Both host genetics and environmental exposures shape the salivary microbiota; however, the relative contributions of these factors from early life to adulthood remain unclear. To address this, we profiled the salivary microbiota of 3387 twin pairs: 939 infant pairs (9–12...
- Health & MedicineOpen access
ABSTRACT Aim Drug‐target Mendelian randomisation (MR) studies investigate whether genetically proxied modulation of druggable proteins affects the risk of periodontitis, thereby identifying potential pharmacological targets. Methods A systematic review was conducted following PRI...