Sichuang Tan

NINJ1 in regulated cell death and cancer: a plasma membrane rupture executor with dual roles in tumor progression

To elucidate the molecular structure, oligomerization mechanisms, and roles of Ninjurin-1 (NINJ1) in regulated cell death (RCD) pathways (pyroptosis, necroptosis, ferroptosis, secondary necrosis, PANoptosis) and its dual role in cancer (tumor suppressor vs. pro-tumor factor). Sys...