Sichao Ren

Structural Basis for the Immunological Paradox of a High-Affinity Yet Non-Immunogenic MHC-I Epitope from Cryptosporidium parvum

Cryptosporidium parvum is an important apicomplexan parasite that causes severe diarrheal disease in children and immunocompromised individuals. However, the structural basis for the limited immunogenicity of its T-cell epitopes remains poorly understood. This study integrates st...