Si Chen

Electrochemical Cytosensor with Dual-Site Recognition Fabricated by In Situ Catalase-Encapsulated Metal–Organic Frameworks for Isolation and Detection of Circulating Tumor Cells in Whole Blood

Abstract Circulating tumor cells (CTCs) are critical biomarkers for cancer prognosis and treatment monitoring, yet their detection remains challenging due to low abundance and phenotypic heterogeneity. Herein, we developed a dual-aptamer-conjugated electrochemical cytosensor usin...

Tripolyphosphate-MediatedInterfacial Electronic ReconfigurationBoosts •OH Production and Redirects Mineral EvolutionDuring FeS Oxygenation

Abstract Oxygenation of mackinawite (FeS) at redox interfaces constitutes a key biogeochemical process that generates hydroxyl radicals (•OH) and facilitates contaminant attenuation. However, the influence of common inorganic ligands such as tripolyphosphate (TPP) on interfacial...