Shuangzhu Yue

DDX3X forms a complex with METTL3 to promote glioma progression via tumor immune microenvironment remodeling

Methyltransferase-like 3 (METTL3) is the key catalytic subunit of the N6-adenosine methyltransferase complex regulating N6-methyladenosine (m6A) modification of mRNA in mammalian cells. Although METTL3 expression is elevated in multiple cancers, the regulatory mechanisms are stil...