Shuangli Zhu

Antifibrotic hydrogel strategies for scarless tissue regeneration: mechanisms, design, and application

Tissue repair is a highly coordinated process, yet dysregulated fibrosis often diverts healing toward scar formation, resulting in permanent structural and functional impairment. Achieving scarless regeneration requires precise modulation of the wound microenvironment to support...

A Hierarchical Hydrogel Modulates Immune‐Mechanical Microenvironments to Spatiotemporally Reprogram Fibroblasts for Scarless Diabetic Wound Healing

ABSTRACT Fibrosis remains a major challenge in wound repair due to the dual role of fibroblast in tissue regeneration and fibrotic deposition. Early fibroblast activation supports wound closure, whereas sustained activation during remodeling drives fibrosis, making precise tempor...