Shuang Zhang

MH-Penile-002: a phase II, prospective, single-arm trial of neoadjuvant anti-EGFR antibody-drug conjugate plus PD-1 inhibitor in penile cancer with challenging penile preservation or regional lymph node metastasis

Emerging evidence suggests that combinations of antibody-drug conjugates (ADCs) and immune checkpoint inhibitors (ICIs) may be effective for advanced penile squamous cell carcinoma (PSCC). These findings support the translation of this strategy into the neoadjuvant setting, offer...

MdKIM1-MdMYB306 enhances apple resistance to Cytospora mali via brassinosteroid biosynthesis under sufficient potassium status

Potassium (K) supplementation enhances apple (Malus ×domestica) resistance to Cytospora mali, thereby reducing apple Cytospora canker occurrence in the field. Nevertheless, the molecular mechanisms underlying this K-enhanced resistance remain largely unelucidated. Here, we found...